江苏特聘教授/博士/硕士生导师
研究领域：化学生物学
招生方向：清洁能源材料开发及利用
电子邮箱：njxzc_chengj@163.com
办公地址：理科组团C楼322室
教育与工作经历：
2001.09-2005.06 南京大学，本科
2005.09-2008.06 南京大学，硕士
2008.09-2013.12 美国Boston College，博士
2014.07-2020.07 美国Human BioMolecular Research Institute，博士后/研究员
2021.01-至今，南京晓庄学院，教师
荣誉与获奖情况：
1. 2024年，校第十二届师德先进个人
2. 2024年，南京晓庄学院大学生创新大赛高教主赛道本科生创意组三等奖指导老师
3. 2024年，第十三届高校化学教育师范生教学技能测试三等奖指导教师
4. 2023年，入选2023年江苏特聘教授
5. 2023年，2023年南京晓庄学院实录微课教学比赛三等奖
6. 2023年，2023年大学生创新创业训练计划省级重点项目指导老师
7. 2022年，南京晓庄学院第十三届课堂教学优秀奖三等奖
8. 2022年，2022届本科生毕业论文“优秀论文”三等奖指导老师
9.2021年，2021年南京晓庄学院微课教学比赛二等奖
主要科研项目：
1. 国家自然科学基金委员会，青年科学基金项目，新型抗胰腺癌药用活性分子的靶标发现、确认及调控机制研究，2022-01至2025-12，主持
2. 江苏省教育厅，2023年江苏特聘教授（省“双创计划”教育类项目），2023-10至2026.09，主持
代表性科研论文及学术专著：
1. Cheng, Jiongjia*; Zhu, Ting; Liu, Shaoxian; Zhou, Jiayu; Wang, Xiaofeng; Liu, Guangxiang*; Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer. RSC Medicinal Chemistry, 2024 Sep 5. doi: 10.1039/d4md00165f.
2. Cheng, Jiongjia*; Wang, Haiying; Zhang, Yuchi; Wang, Xiaofeng; Liu, Guangxiang*; Advances in crosslinking chemistry and proximity-enabled strategies: deciphering protein complexes and interactions, Organic & Biomolecular Chemistry, 2024, 22(37): 7549-7559.
3. Chen, Jiaqi; Yuan, Xuechun; Yang, Bingxin; Yao, Xueyu; Cheng, Jiongjia*; Chu, Qian*; Application of Twin-Strep Tagging and TurboID Proximity Labeling in Discovery of Microprotein-protein Interactions, ChemistrySelect, 2024, 9(23): e202401782.
4. Cheng, Jiongjia; Zhou, Junlong; Kong, Lingyan; Wang, Haiying; Zhang, Yuchi; Wang, Xiaofeng; Liu, Guangxiang*; Chu, Qian*; Stabilized cyclic peptides as modulators of protein-protein interactions: promising strategies and biological evaluation. RSC Medicinal Chemistry, 2023, 14(12):2496-2508.
5. Cheng, Jiongjia*; Wang, Xiaofeng; Yuan, Xuechun; Liu, Guangxiang; Chu, Qian*; Emerging roles of exosome-derived biomarkers in cancer theranostics: messages from novel protein targets, American Journal of Cancer Research, 2022, 12(5): 2226-2248.
6. Cheng, Jiongjia#; Tsuda, Masanao#; Okolotowicz, Karl J.; Dwyer, Mary; Bushway, Paul J.; Colas, Alexandre R.; Lancman, Joseph J.; Schade, Dennis; Perea-Gil, Isaac; Bruyneel, Arne A.N.; Lee, Jaechol; Vadgama, Nirmal; Quach, Justine; McKeithan, Wesley L.; Biechele, Travis L.; Wu, Joseph C.; Moon, Randall T.; Dong, Duc Si; Karakikes, Ioannis; Cashman, John R.; Mercola, Mark*; Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness, Cell Chemical Biology, 2021, 28(5): 625-635.
7. Cheng, Jiongjia*; Cashman, John R.; Pancreatic cancer drug-sensitivity predicted by synergy of PAWI-2 and protein biomarker expression, Investigational New Drugs, 2021, 39(1):131-141.
8. Cheng, Jiongjia*; Cashman, John R.; PAWI-2 overcomes tumor stemness and drug resistance via cell cycle arrest in integrin β3-KRAS-dependent pancreatic cancer stem cells, Scientific Reports, 2020, 10(1): 9162.
9. Cheng, Jiongjia*; Cashman, John R.; PAWI-2: A Novel Inhibitor for Eradication of Cancer Medicinal Chemistry Research, 2020, 29, 1147-1159.
10. Cheng, Jiongjia*; Okolotowicz, Karl J.; Ryan, Daniel; Mose, Evangeline; Lowy, Andrew M.; Cashman, John R.; Inhibition of invasive pancreatic cancer: Restoring cell apoptosis by activating mitochondrial p53, American Journal of Cancer Research, 2019, 9(2): 390-405.
11.Cheng, Jiongjia*; Dwyer, Mary; Okolotowicz, Karl J.; Mercola, Mark; Cashman, John R.; A novel inhibitor targets both Wnt signaling and ATM/p53 in colorectal cancer, Cancer Research, 2018, 78(17): 5072-5083.
